Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 13/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938332 | 0.87 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL6469886 | 0.87 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL28713523 | 0.82 | METTL3 (0.60) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL29365731 | 0.82 | METTL3 (0.60) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL23547979 | 0.80 | ADORA3 (0.75) | DOT1L | |
| SCHEMBL3369124 | 0.80 | ADORA3 (0.75) | DOT1L | |
| SCHEMBL21418864 | 0.80 | ADORA3 (0.75) | DOT1L | |
| SCHEMBL1066939 | 0.80 | ADORA3 (0.75) | DOT1L | |
| SCHEMBL16359953 | 0.80 | ADORA3 (0.75) | DOT1L | |
| SCHEMBL29748808 | 0.80 | ADORA3 (0.75) | DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079479-B1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2014-11-26 | — | — | EP | disclosed |