Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.60 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.60 |
| ▸ | ADK | P55263 | 11/20 | 0.58 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713523 | 1.00 | METTL3 (0.60) | METTL3PRMT5ADKDOT1LNPC1 | |
| SCHEMBL6469886 | 0.90 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20938332 | 0.90 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL23313201 | 0.89 | ADK (0.64) | METTL3PRMT5ADKDOT1LNPC1 | |
| SCHEMBL15948775 | 0.88 | PRMT5 (0.60) | PRMT5ADKDOT1LNPC1GALR3 | |
| SCHEMBL23313207 | 0.87 | PRMT5 (0.66) | METTL3PRMT5ADK | |
| SCHEMBL24293493 | 0.87 | ADK (0.67) | METTL3PRMT5ADKDOT1LNPC1 | |
| SCHEMBL29365519 | 0.87 | ADK (0.67) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL29365390 | 0.87 | ADK (0.67) | METTL3PRMT5ADKDOT1LNPC1 | |
| SCHEMBL16242266 | 0.82 | ADK (0.55) | METTL3PRMT5ADKDOT1LNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220233566-A1 | NOVEL CARBONATE COMPOUND HAVING PYRROLOPYRIMIDINE SKELETON OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2022-07-28 | — | — | US | disclosed |
| CN-114008064-A | Novel phosphate ester compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-02-01 | — | — | CN | disclosed |
| CN-113993877-A | Novel carbonate compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220233566-A1 | NOVEL CARBONATE COMPOUND HAVING PYRROLOPYRIMIDINE SKELETON OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TYMP, SLC20A1, MGMT | METTL3 1710/4885PRMT5 903/4885ADK 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.