SCHEMBL16243791

SCHEMBL16243791

C=C(C)C(=O)OCCCOC(=O)c1ccc(C(=O)O)c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.48
POLB P06746 2/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TSHR P16473 9/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 3/20 0.43
CYP3A4 P08684 2/20 0.43
TP53 P04637 1/20 0.43
ALDH1A1 P00352 7/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 4/20 0.42
KDM4A O75164 1/20 0.42
KDM4C Q9H3R0 1/20 0.42
HRH3 Q9Y5N1 1/20 0.40
HSD17B10 Q99714 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16243602 0.94 TSHR (0.44) TDP1POLBAPEX1HTTTSHR
SCHEMBL194453 0.87 TSHR (0.55) TDP1POLBAPEX1HTTTSHR
SCHEMBL28304537 0.86 TSHR (0.54) TDP1POLBAPEX1HTTTSHR
SCHEMBL194750 0.85 TSHR (0.58) TDP1POLBAPEX1HTTTSHR
SCHEMBL645003 0.84 TSHR (0.62) TDP1POLBAPEX1HTTTSHR
SCHEMBL16243790 0.83 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL16243474 0.83 MAPK1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL10064079 0.82 KDM4E (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL27953992 0.81 TSHR (0.68) TDP1POLBTSHRL3MBTL1MAPK1
SCHEMBL4783599 0.81 TSHR (0.56) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9177819-B2 Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPORATION (JP) 2015-11-03 US disclosed
US-20140349485-A1 METHOD FOR MANUFACTURING SILICON SUBSTRATE HAVING TEXTURED STRUCTURE TOKUYAMA CORPORATION a corporation 2014-11-27 US disclosed