Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962588 | 0.88 | CTSS (0.49) | CTSSCTSKMIFCA1CA2 | |
| SCHEMBL2928886 | 0.88 | ALDH1A1 (0.57) | CTSSCTSKHTTCYP1A2CYP2C9 | |
| SCHEMBL10240502 | 0.87 | CTSK (0.62) | CTSSCTSKHTTCYP1A2CYP2C9 | |
| SCHEMBL27833801 | 0.87 | CTSK (0.62) | CTSSCTSKHTTCYP1A2CYP2C9 | |
| SCHEMBL1554126 | 0.87 | CTSS (0.48) | CTSSCTSKMAPTMIFESR1 | |
| SCHEMBL1554122 | 0.87 | CTSS (0.48) | CTSSCTSKMAPTMIFESR1 | |
| SCHEMBL2582580 | 0.87 | CTSS (0.48) | CTSSCTSKMAPTMIFESR1 | |
| SCHEMBL11638205 | 0.87 | CTSK (0.47) | CTSSCTSKCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1931651 | 0.86 | CTSK (0.49) | CTSSCTSKHTTCYP1A2CYP2C9 | |
| SCHEMBL5814774 | 0.85 | CTSS (0.47) | CTSSCTSKHTTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940928-B2 | Method of synthesizing levorotatory p-hydroxyphenylglycine compounds | Henan Newland Pharmaceutical Co., Ltd. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-8940928-B2 | Method of synthesizing levorotatory p-hydroxyphenylglycine compounds | Henan Newland Pharmaceutical Co., Ltd. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-8940928-B2 | Method of synthesizing levorotatory p-hydroxyphenylglycine compounds | Henan Newland Pharmaceutical Co., Ltd. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-20140350295-A1 | METHOD OF SYNTHESIZING LEVOROTATORY P-HYDROXYPHENYLGLYCINE COMPOUNDS | NEWLAND PHARMACEUTICAL CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| US-20140350295-A1 | METHOD OF SYNTHESIZING LEVOROTATORY P-HYDROXYPHENYLGLYCINE COMPOUNDS | NEWLAND PHARMACEUTICAL CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| US-20140350295-A1 | METHOD OF SYNTHESIZING LEVOROTATORY P-HYDROXYPHENYLGLYCINE COMPOUNDS | NEWLAND PHARMACEUTICAL CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350295-A1 | METHOD OF SYNTHESIZING LEVOROTATORY P-HYDROXYPHENYLGLYCINE COMPOUNDS | COMT, HPD, PAH | CTSS 2162/4885CTSK 2772/4885HTT 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.