Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268963 | 0.88 | L3MBTL1 (0.59) | AKR1C2AKR1C1POLBL3MBTL1CNR2 | |
| SCHEMBL30361685 | 0.88 | L3MBTL1 (0.59) | AKR1C2AKR1C1POLBL3MBTL1CNR2 | |
| SCHEMBL121422 | 0.85 | HNF4A (0.63) | AKR1C2AKR1C1POLBL3MBTL1HNF4A | |
| SCHEMBL13504679 | 0.85 | HNF4A (0.50) | AKR1C2AKR1C1POLBL3MBTL1SYK | |
| SCHEMBL6849570 | 0.85 | HNF4A (0.69) | AKR1C2AKR1C1POLBL3MBTL1CNR2 | |
| SCHEMBL23908687 | 0.82 | AKR1C2 (0.48) | AKR1C2AKR1C1POLBL3MBTL1CNR2 | |
| SCHEMBL2556585 | 0.82 | NR1H4 (0.46) | AKR1C2AKR1C1POLBL3MBTL1SYK | |
| SCHEMBL5046158 | 0.81 | MYC (0.59) | AKR1C2AKR1C1POLBL3MBTL1HNF4A | |
| SCHEMBL2559209 | 0.81 | TRIM24 (0.53) | POLBL3MBTL1SYKHNF4AALDH1A1 | |
| SCHEMBL15515383 | 0.81 | DHODH (0.51) | AKR1C2AKR1C1POLBL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238637-B2 | Stable polymorphic forms of compound as hypoxia mimetics, and uses thereof | BEIJING BETTA PHARMACEUTICALS CO., LTD (CN) | 2016-01-19 | — | — | US | disclosed |
| US-20140343137-A1 | Stable Polymorphic Forms of Compound as Hypoxia Mimetics, and Uses Thereof | BEIJING BETTA PHARMACEUTICALS CO., LTD. (CN) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343137-A1 | Stable Polymorphic Forms of Compound as Hypoxia Mimetics, and Uses Thereof | HIF1A, HIF1AN, COXFA4L2 | AKR1C2 497/4885AKR1C1 594/4885POLB 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.