SCHEMBL268963

SCHEMBL268963

Cc1cccc(-c2ccccc2C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
MYC P01106 1/20 0.56
POLB P06746 2/20 0.56
HNF4A P41235 1/20 0.53
AKR1C2 P52895 1/20 0.53
AKR1C1 Q04828 1/20 0.53
CNR2 P34972 1/20 0.53
ALDH1A1 P00352 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MCL1 Q07820 3/20 0.51
BAD Q92934 1/20 0.51
KMO O15229 2/20 0.50
LDHA P00338 1/20 0.50
KDM4E B2RXH2 2/20 0.49
GAA P10253 1/20 0.49
HSD17B10 Q99714 1/20 0.49
LPAR1 Q92633 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361685 1.00 L3MBTL1 (0.59) L3MBTL1MYCPOLBHNF4AAKR1C2
SCHEMBL16247703 0.88 AKR1C2 (0.51) L3MBTL1MYCPOLBHNF4AAKR1C2
SCHEMBL689031 0.87 HNF4A (0.62) L3MBTL1MYCHNF4AALDH1A1MEN1
SCHEMBL6849570 0.86 HNF4A (0.69) L3MBTL1MYCPOLBHNF4AAKR1C2
SCHEMBL31241243 0.86 HDAC7 (0.57) L3MBTL1POLBAKR1C2AKR1C1CNR2
SCHEMBL10911513 0.85 MYC (0.55) L3MBTL1MYCPOLBHNF4AALDH1A1
SCHEMBL10954387 0.85 CNR2 (0.64) L3MBTL1POLBCNR2ALDH1A1KMT2A
SCHEMBL6667275 0.84 BCAT2 (0.65) L3MBTL1CNR2ALDH1A1KDM4ESMN1; SMN2
SCHEMBL7252300 0.83 ACMSD (0.59) L3MBTL1MYCHNF4AALDH1A1MCL1
SCHEMBL735163 0.83 L3MBTL1 (0.52) L3MBTL1POLBCNR2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10787432-B2 N-[(pyridyloxy)propanyl]benzamides BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2020-09-29 US disclosed
EP-3442958-B1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2020-05-06 EP disclosed
EP-3442958-B1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2020-05-06 EP disclosed
US-20190112291-A1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) 2019-04-18 US disclosed
CN-105555761-B Biphenyl derivatives and process for preparing the same 东亚ST 株式会社 2018-12-11 CN disclosed
EP-3029026-B1 NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME DONG A ST CO LTD (KR) 2018-12-05 EP disclosed
US-10081593-B2 Alkyl aromatic hydroalkylation for the production of plasticizers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-09-25 US disclosed
US-20180022689-A1 Alkyl Aromatic Hydroalkylation For The Production of Plasticizers EXXONMOBIL CHEMICAL PATENTS INC 2018-01-25 US disclosed
US-9828339-B2 Biphenyl derivatives and methods for preparing same DONG-A ST CO., LTD (KR) 2017-11-28 US disclosed
US-9815767-B2 Alkyl aromatic hydroalkylation for the production of plasticizers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-11-14 US disclosed
US-5710150-A ARGININE VASOPRESSIN ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-01-20 US disclosed
EP-0676298-B1 Transparent recording medium and process for its production JUJO PAPER CO LTD (JP) 1997-03-05 EP disclosed
EP-0737722-A2 New indoaniline metal complex, process for their production, and transparent recording medium and optical recording medium by use thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-16 EP disclosed
EP-0520404-B1 Transparent recording medium JUJO PAPER CO LTD (JP) 1996-09-11 EP disclosed
EP-0716083-A1 BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-06-12 EP disclosed
US-5482913-A CARBONATE TYPE BLOCKED COLOR DEVELOPER, LASER RECORDING NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-01-09 US disclosed
EP-0676298-A1 Transparent recording medium and process for its production NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-10-11 EP disclosed
US-5434119-A TRANSPORT RECORDING LAYER COMPRISING DEVELOPER FORMED BY BLOCKING HYDROXYL GROUP WITH DEVELOPING FUNCTION JUJO PAPER CO., LTD. (JP) 1995-07-18 US disclosed
EP-0605149-A2 Recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-07-06 EP disclosed
EP-0520404-A1 Transparent recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1992-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022689-A1 Alkyl Aromatic Hydroalkylation For The Production of Plasticizers ALKBH3, AHR, ADH1A L3MBTL1 1987/4885MYC 679/4885POLB 2182/4885
US-10787432-B2 N-[(pyridyloxy)propanyl]benzamides HCRTR1, HCRTR2, CNR1 L3MBTL1 4503/4885MYC 3984/4885POLB 3928/4885
US-20190112291-A1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES HCRTR1, HCRTR2, CNR1 L3MBTL1 4609/4885MYC 3881/4885POLB 4434/4885
US-10081593-B2 Alkyl aromatic hydroalkylation for the production of plasticizers ALKBH3, AHR, ADH1A L3MBTL1 1987/4885MYC 679/4885POLB 2182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.