SCHEMBL16248346

SCHEMBL16248346

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nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GNPAT O15228 1/20 0.46
▸ MMP3 P08254 6/20 0.38
▸ MME P08473 2/20 0.36
▸ BMP1 P13497 2/20 0.34
▸ MMP9 P14780 3/20 0.34
▸ ENPEP Q07075 5/20 0.33
▸ FOLH1 Q04609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13555664 0.84 GNPAT (0.43) GNPATMMEBMP1ENPEP
SCHEMBL13555660 0.84 GNPAT (0.43) GNPATMMEBMP1FOLH1
SCHEMBL13555658 0.83 GNPAT (0.48) GNPATMMEBMP1ENPEP
SCHEMBL29311779 0.78 MME (0.37) GNPATMMP3MMEENPEP
SCHEMBL13555659 0.76 GNPAT (0.35) GNPATMME
SCHEMBL17178036 0.74 BMP1 (0.42) MMP3BMP1
SCHEMBL1688067 0.74 CA2 (0.35) GNPATMMEFOLH1
SCHEMBL18127347 0.74 SLC22A6 (0.35) GNPAT
SCHEMBL16383645 0.74 SLC22A6 (0.35) GNPAT
SCHEMBL14959392 0.74 SLC22A6 (0.35) GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9415114-B2 Conformations of divergent peptides with mineral binding affinity KAOHSIUNG MEDICAL UNIVERSITY (TW) 2016-08-16 — — US disclosed
US-9314533-B2 Conformations of divergent peptides with mineral binding affinity KAOHSIUNG MEDICAL UNIVERSITY (TW) 2016-04-19 — — US disclosed
US-20150320876-A1 CONFORMATIONS OF DIVERGENT PEPTIDES WITH MINERAL BINDING AFFINITY KAOHSIUNG MEDICAL UNIVERSITY (TW) 2015-11-12 — — US disclosed
US-20140377212-A1 CONFORMATIONS OF DIVERGENT PEPTIDES WITH MINERAL BINDING AFFINITY KAOHSIUNG MEDICAL UNIVERSITY (TW) 2014-12-25 — — US disclosed
US-8889828-B2 Conformations of divergent peptides with mineral binding affinity KAOHSIUNG MEDICAL UNIVERSITY (TW) 2014-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140377212-A1 CONFORMATIONS OF DIVERGENT PEPTIDES WITH MINERAL BINDING AFFINITY SDF4, CALCB, CALCA GNPAT 2505/4885MMP3 3109/4885MME 1055/4885
US-20150320876-A1 CONFORMATIONS OF DIVERGENT PEPTIDES WITH MINERAL BINDING AFFINITY SDF4, CALCB, CALCA GNPAT 2505/4885MMP3 3109/4885MME 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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