SCHEMBL16250098

SCHEMBL16250098

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccc5c(sc6ccccc65)c3-4)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
MAPT P10636 6/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
NTSR1 P30989 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
AGTR1 P30556 4/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18731668 0.99 ALOX5 (0.35) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL20224325 0.99 ALOX5 (0.35) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL16250095 0.97 ALOX5 (0.36) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL20224281 0.96 MAPT (0.34) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL14681623 0.95 ALOX5 (0.36) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL16250111 0.95 ALOX5 (0.36) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL18731666 0.94 ALOX5 (0.36) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL20224314 0.94 ALOX5 (0.36) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL18731693 0.93 ALOX5 (0.35) ALOX5MAPTMEN1KMT2AALDH1A1
SCHEMBL20224317 0.93 ALOX5 (0.35) ALOX5MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-09-05 US disclosed
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-09-05 US disclosed
US-20210328155-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-10-21 US disclosed
EP-3119767-B1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2019-07-10 EP disclosed
US-20170117485-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-04-27 US disclosed
US-20170117485-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-04-27 US disclosed
WO-2015142036-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-09-24 WO disclosed
WO-2014185751-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328155-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, MT-ND4, GPX4 ALOX5 1711/4885MAPT 1503/4885MEN1 1560/4885
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same SOD1, MT-ND4, GPX4 ALOX5 1711/4885MAPT 1503/4885MEN1 1560/4885
US-20170117485-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, MT-ND4, GPX4 ALOX5 1711/4885MAPT 1503/4885MEN1 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.