Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874871 | 1.00 | LMNA (0.76) | LMNAHPGDL3MBTL1KDM4EPOLB | |
| SCHEMBL28448203 | 0.94 | HPGD (0.71) | LMNAHPGDL3MBTL1KDM4ETDP1 | |
| SCHEMBL24983425 | 0.90 | HPGD (0.84) | LMNAHPGDKDM4ESMPD1HDAC1 | |
| SCHEMBL30892445 | 0.90 | HPGD (0.84) | LMNAHPGDKDM4ESMPD1HDAC1 | |
| SCHEMBL1919991 | 0.89 | LMNA (0.72) | LMNAHPGDL3MBTL1KDM4ETDP1 | |
| SCHEMBL21738207 | 0.89 | HPGD (0.77) | LMNAHPGDKDM4ESMPD1HDAC1 | |
| SCHEMBL6865198 | 0.88 | HPGD (0.71) | LMNAHPGDL3MBTL1KDM4ESMPD1 | |
| SCHEMBL15476331 | 0.88 | HPGD (0.71) | LMNAHPGDL3MBTL1KDM4ESMPD1 | |
| SCHEMBL16250484 | 0.87 | LMNA (1.00) | LMNAHPGDL3MBTL1KDM4EPOLB | |
| SCHEMBL18397048 | 0.86 | HPGD (0.82) | LMNAHPGDKDM4EGAASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417766-B | Synthesis method of 3-hydroxy-4, 5-dimethoxy benzoic acid tert-butyl ester | 天津药明康德新药开发有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115417766-A | Synthesis method of 3-hydroxy-4, 5-dimethoxy benzoic acid tert-butyl ester | 天津药明康德新药开发有限公司 | 2022-12-02 | — | — | CN | disclosed |