Sugi Predict

Sugi Predict / Compounds / SCHEMBL4874871

SCHEMBL4874871

SCHEMBL4874871

COC(=O)c1cc(O)c(O)c(OCc2ccccc2)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.76
▸ HPGD P15428 2/20 0.76
▸ L3MBTL1 Q9Y468 3/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ POLB P06746 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ NFKB1 P19838 1/20 0.56
▸ XDH P47989 1/20 0.56
▸ GFER P55789 1/20 0.56
▸ NFKB2 Q00653 1/20 0.56
▸ RELA Q04206 1/20 0.56
▸ FUT7 Q11130 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ SMPD1 P17405 1/20 0.53
▸ HDAC1 Q13547 1/20 0.53
▸ HDAC8 Q9BY41 1/20 0.53
▸ HDAC6 Q9UBN7 1/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ RAB9A P51151 2/20 0.51
▸ NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30102539 1.00 LMNA (0.76) LMNAHPGDL3MBTL1KDM4EPOLB
SCHEMBL28448203 0.94 HPGD (0.71) LMNAHPGDL3MBTL1KDM4ETDP1
SCHEMBL24983425 0.90 HPGD (0.84) LMNAHPGDKDM4ESMPD1HDAC1
SCHEMBL30892445 0.90 HPGD (0.84) LMNAHPGDKDM4ESMPD1HDAC1
SCHEMBL1919991 0.89 LMNA (0.72) LMNAHPGDL3MBTL1KDM4ETDP1
SCHEMBL21738207 0.89 HPGD (0.77) LMNAHPGDKDM4ESMPD1HDAC1
SCHEMBL6865198 0.88 HPGD (0.71) LMNAHPGDL3MBTL1KDM4ESMPD1
SCHEMBL15476331 0.88 HPGD (0.71) LMNAHPGDL3MBTL1KDM4ESMPD1
SCHEMBL16250484 0.87 LMNA (1.00) LMNAHPGDL3MBTL1KDM4EPOLB
SCHEMBL18397048 0.86 HPGD (0.82) LMNAHPGDKDM4EGAASMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9644074-B2 Benzene polycarboxylic acid compounds and their use as drug RINNOVATION APS (DK) 2017-05-09 — — US claimed
EP-2831151-B1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDINNOVATION APS (DK) 2016-12-14 — — EP claimed
US-20160017104-A1 Benzene Polycarboxylic Acid Compounds and Their Use as Drug RDINNOVATION APS (DK) 2016-01-21 — — US claimed
EP-2831151-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDInnovation ApS (DK) 2015-02-04 — — EP claimed
WO-2013143549-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDINNOVATION APS (DK) 2013-10-03 — — WO claimed
CN-115417766-B Synthesis method of 3-hydroxy-4, 5-dimethoxy benzoic acid tert-butyl ester 天津药明康德新药开发有限公司 2024-05-17 — — CN disclosed
CN-115417766-A Synthesis method of 3-hydroxy-4, 5-dimethoxy benzoic acid tert-butyl ester 天津药明康德新药开发有限公司 2022-12-02 — — CN disclosed
CN-110294732-B Pharmaceutical compound for treating liver diseases and application thereof 江苏新元素医药科技有限公司 2021-10-26 — — CN disclosed
WO-2020035058-A1 PHARMACEUTICAL COMPOUNDS FOR TREATING LIVER DISEASES AND APPLICATION THEREOF 江苏新元素医药科技有限公司 2020-02-20 — — WO disclosed
WO-2020035058-A1 PHARMACEUTICAL COMPOUNDS FOR TREATING LIVER DISEASES AND APPLICATION THEREOF 江苏新元素医药科技有限公司 2020-02-20 — — WO disclosed
US-9644074-B2 Benzene polycarboxylic acid compounds and their use as drug RINNOVATION APS (DK) 2017-05-09 — — US disclosed
US-9644074-B2 Benzene polycarboxylic acid compounds and their use as drug RINNOVATION APS (DK) 2017-05-09 — — US disclosed
US-20160017104-A1 Benzene Polycarboxylic Acid Compounds and Their Use as Drug RDINNOVATION APS (DK) 2016-01-21 — — US disclosed
EP-2831151-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDInnovation ApS (DK) 2015-02-04 — — EP disclosed
WO-2013143549-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDINNOVATION APS (DK) 2013-10-03 — — WO disclosed
US-20080070850-A1 GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE THE PENN STATE RESEARCH FOUNDATION (US) 2008-03-20 — — US disclosed
US-7288273-B1 Gallotannins and ellagitannins as regulators of cytokine release THE PENN STATE RESEARCH FOUNDATION (US) 2007-10-30 — — US disclosed
EP-1232169-A1 GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE THE PENN STATE RESEARCH FOUNDATION (US) 2002-08-21 — — EP disclosed
WO-2001036436-A1 GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE THE PENN STATE RESEARCH FOUNDATION (US) 2001-05-25 — — WO disclosed
US-5198571-A MONOFUNCTIONALIZATION OF PHENOLIC HYDROXY ONTO A POLYPHENOL ROUSSEL UCLAF (FR) 1993-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080070850-A1 GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE IL2, IL6, TNF LMNA 4844/4885HPGD 536/4885L3MBTL1 4389/4885
US-20160017104-A1 Benzene Polycarboxylic Acid Compounds and Their Use as Drug PAH, HPD, PLOD2 LMNA 928/4885HPGD 374/4885L3MBTL1 4429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.