Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43576 | 0.87 | PSMB8 (0.35) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL31522720 | 0.85 | PSMB8 (0.34) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL13069250 | 0.84 | PSMB8 (0.35) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL11125521 | 0.84 | LMNA (0.34) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL22777675 | 0.83 | SMN1; SMN2 (0.36) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL9333307 | 0.83 | MGLL (0.33) | MGLL | |
| SCHEMBL34383 | 0.83 | SMN1; SMN2 (0.36) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL290461 | 0.83 | SMN1; SMN2 (0.40) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL24152468 | 0.83 | PSMB8 (0.31) | PSMB8PSMB5 | |
| SCHEMBL905722 | 0.82 | SMN1; SMN2 (0.42) | PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889101-B2 | Dendrimer based nanodevices for therapeutic and imaging purposes | WAYNE STATE UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |