SCHEMBL9333307

SCHEMBL9333307

O=C(CF)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.33
ALOX12 P18054 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16254124 0.83 PSMB8 (0.33) MGLL
SCHEMBL2618714 0.82 MGLL (0.34) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL43576 0.82 PSMB8 (0.35) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL31522720 0.80 PSMB8 (0.34) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL3805679 0.80 MGLL (0.33) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL11125521 0.79 LMNA (0.34) MGLL
SCHEMBL34383 0.78 SMN1; SMN2 (0.36) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL17756748 0.78 ALDH1A1 (0.38) MGLLADORA3ADORA2AADORA2B
SCHEMBL1681951 0.78 MGLL (0.33) MGLLALOX12ADORA3ADORA2AADORA2B
SCHEMBL22777675 0.78 SMN1; SMN2 (0.36) MGLLALOX12ADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114636-B2 Labeling and detection of nucleic acids Life Technologies Corporation (US) 2012-02-14 US disclosed
US-20080050731-A1 LABELING AND DETECTION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2008-02-28 US disclosed
EP-0359996-B1 Synthetic amino acid-and/or peptide-containing graft copolymers AL MARZOOK UNITED COMMERCIAL C (KW) 1994-04-13 EP disclosed
EP-0359996-A2 Synthetic amino acid-and/or peptide-containing graft copolymers Al Marzook United Commercial Co. (KW) 1990-03-28 EP disclosed
US-4908404-A Water soluble high molecular weight cationic graft polymer BIOPOLYMERS, INC. (US) 1990-03-13 US disclosed