Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16255704 | 0.87 | KMT2A (0.52) | KMT2AMEN1TSHRMAPTMC4R | |
| SCHEMBL12141552 | 0.86 | MTOR (0.47) | MTORKMT2AMEN1MAPTDRD2 | |
| SCHEMBL7923613 | 0.85 | MAPT (0.53) | KMT2AMEN1TSHRMAPTMC4R | |
| SCHEMBL16255781 | 0.84 | TSHR (0.65) | MTORKMT2AMEN1TSHRMAPT | |
| SCHEMBL16255766 | 0.84 | MTOR (0.48) | MTORKMT2AMEN1TSHRMAPT | |
| SCHEMBL7923612 | 0.82 | KMT2A (0.44) | MTORKMT2AMEN1TSHRMAPT | |
| SCHEMBL10259980 | 0.80 | ALDH1A1 (0.48) | KMT2AMEN1TSHRMAPTPOLB | |
| SCHEMBL16255671 | 0.78 | MTOR (0.48) | MTORKMT2AMEN1TSHRMAPT | |
| SCHEMBL16255668 | 0.78 | ALDH1A1 (0.46) | MTORKMT2AMEN1TSHRMAPT | |
| SCHEMBL16255767 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889706-B2 | Soluble mTOR complexes and modulators thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-11-18 | — | — | US | disclosed |