SCHEMBL1625599

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15294616	0.86	ALDH1A1 (0.58)	ALDH1A1TSHRNPC1RAB9AFAAH
	SCHEMBL13144362	0.86	ALDH1A1 (0.55)	ALDH1A1TSHRNPC1RAB9AFFAR1
	SCHEMBL14483862	0.85	ALDH1A1 (0.51)	ALDH1A1TSHRNPC1RAB9AMEN1
	SCHEMBL6119949	0.85	FFAR1 (0.52)	ALDH1A1TSHRFFAR1FAAHMEN1
	SCHEMBL6721979	0.84	ALDH1A1 (0.56)	ALDH1A1TSHRNPC1RAB9AFFAR1
	SCHEMBL28222075	0.84	ESR1 (0.46)	ALDH1A1TSHRNPC1RAB9AESR1
	SCHEMBL1509141	0.84	ESR1 (0.46)	ALDH1A1TSHRNPC1RAB9AESR1
	SCHEMBL1789851	0.84	ALDH1A1 (0.53)	ALDH1A1TSHRNPC1RAB9AMEN1
	SCHEMBL18959912	0.83	ALDH1A1 (0.59)	ALDH1A1TSHRNPC1RAB9AMEN1
	SCHEMBL10127207	0.83	KMT2A (0.57)	ALDH1A1TSHRNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.