Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.53 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579243 | 0.89 | MARS1 (0.58) | MARS1ADORA1P2RY1P2RY2SRC | |
| SCHEMBL2761284 | 0.89 | MARS1 (0.74) | MARS1ADORA1P2RY1P2RY2SRC | |
| SCHEMBL16256550 | 0.85 | MARS1 (0.54) | MARS1ADORA1P2RY1P2RY2SRC | |
| SCHEMBL15527469 | 0.84 | ADORA1 (0.55) | ADORA1P2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL14853916 | 0.83 | P2RY1 (0.64) | ADORA1P2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL16256549 | 0.83 | RXFP1 (0.56) | MARS1ADORA1P2RX1P2RX3P2RX4 | |
| SCHEMBL12226792 | 0.82 | ADORA3 (0.77) | ADORA1SMN1; SMN2TAS1R3TAS1R1ADORA3 | |
| SCHEMBL12200092 | 0.82 | ADORA3 (0.77) | ADORA1SMN1; SMN2TAS1R3TAS1R1ADORA3 | |
| SCHEMBL15080479 | 0.82 | ADORA3 (0.77) | ADORA1SMN1; SMN2TAS1R3TAS1R1ADORA3 | |
| SCHEMBL1796966 | 0.82 | ATG7 (0.63) | ADORA1P2RY1P2RY2SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895530-B2 | Method of reducing intraocular pressure in humans | INOTEK PHARMACEUTICALS CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |