Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306362 | 0.85 | LMNA (0.58) | EGFRABCG2LMNAMEN1GMNN | |
| SCHEMBL16257538 | 0.81 | EGFR (0.61) | EGFRABCG2LMNASYKBRAF | |
| SCHEMBL15033667 | 0.76 | LMNA (0.58) | EGFRABCG2LMNAMEN1GMNN | |
| SCHEMBL14318457 | 0.76 | TP53 (0.65) | EGFRABCG2LMNAMEN1GMNN | |
| SCHEMBL15033805 | 0.73 | SYK (0.58) | EGFRLMNAMEN1GMNNALDH1A1 | |
| SCHEMBL2100607 | 0.72 | EGFR (1.00) | EGFRABCG2LMNAMEN1GMNN | |
| SCHEMBL3918204 | 0.72 | EGFR (0.69) | EGFRABCG2LMNAALDH1A1SYK | |
| Niflumic Acid SCHEMBL4886924 | 0.71 | DHODH (1.00) | LMNAMEN1GMNNALDH1A1TTR | |
| Niflumic Acid SCHEMBL24706 | 0.71 | DHODH (1.00) | LMNAMEN1GMNNALDH1A1TTR | |
| Niflumic Acid SCHEMBL29373503 | 0.71 | DHODH (1.00) | LMNAMEN1GMNNALDH1A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946218-B2 | CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8926915-B2 | Smell-diffusing cell array substrate, apparatus for transferring smell information and electronic device including the apparatus | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-01-06 | — | — | US | disclosed |
| EP-2569295-B1 | NEW CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-11-19 | — | — | EP | disclosed |