SCHEMBL16258131

SCHEMBL16258131

C/C=C/CCc1ccc(-c2ccc(-c3ccc(CC)cc3)c(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.40
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35
KIF11 P52732 1/20 0.33
KCNA3 P22001 2/20 0.33
HCAR2 Q8TDS4 2/20 0.33
GRIA4 P48058 1/20 0.33
CHKA P35790 1/20 0.33
GCGR P47871 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAOB P27338 1/20 0.32
FDFT1 P37268 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
CYP17A1 P05093 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13577669 1.00 RARB (0.40) RARBRARARARGTAAR1KIF11
SCHEMBL15180192 1.00 RARB (0.40) RARBRARARARGTAAR1KIF11
SCHEMBL17402085 0.92 RARB (0.42) RARBRARARARGTAAR1KIF11
SCHEMBL15180194 0.92 RARB (0.42) RARBRARARARGTAAR1KIF11
SCHEMBL18416768 0.89 RARB (0.49) RARBRARARARGFDFT1S1PR1
SCHEMBL18416759 0.89 RARB (0.49) RARBRARARARGFDFT1S1PR1
SCHEMBL18458484 0.89 GPR52 (0.40) RARBRARARARGTAAR1KCNA3
SCHEMBL20849604 0.89 GPR52 (0.40) RARBRARARARGTAAR1KCNA3
SCHEMBL11957385 0.89 FFAR4 (0.39) RARBRARARARGTAAR1KIF11
SCHEMBL16258133 0.89 FFAR4 (0.39) RARBRARARARGTAAR1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-20210223635-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-07-22 US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 US disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
EP-2845892-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC Corporation (JP) 2015-03-11 EP disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
EP-2837670-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC Corporation (JP) 2015-02-18 EP disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed
EP-2806011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN RARB 3761/4885RARA 1982/4885RARG 3552/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885RARA 3675/4885RARG 3904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.