Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.35 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521955 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL19770015 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL15982017 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL12958081 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL17191644 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL25480878 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL25763672 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL19798073 | 1.00 | OGA (0.43) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL10024713 | 0.95 | OGA (0.41) | OGACYP2D6THRBHSD17B10CA2 | |
| SCHEMBL16923234 | 0.95 | OGA (0.41) | OGACYP2D6THRBHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | JIANGSU VANGUARD PHARMACEUTICAL CO., LTD. (CN) | 2023-07-04 | — | — | US | disclosed |
| US-20160256481-A1 | USE OF WATER SOLUBLE PLATINUM COMPLEX IN PREPARING DRUGS FOR PREVENTION AND TREATMENT OF CANCERS | GUDUI BIOPHARMA TECHNOLOGY INC. (CN) | 2016-09-08 | — | — | US | disclosed |
| US-20150051387-A1 | WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | GUDUI BIOPHARMA TECHNOLOGY INC. (CN) | 2015-02-19 | — | — | US | disclosed |
| US-20150011740-A1 | FLUORINE-CONTAINING WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | GUDUI BIOPHARMA TECHNOLOGY INC. (CN) | 2015-01-08 | — | — | US | disclosed |
| US-20140349955-A1 | USE OF FLUORINE-CONTAINING WATER SOLUBLE PLATINUM COMPLEX IN PREPARING DRUGS FOR PREVENTION AND TREATMENT OF CANCERS | GUDUI BIPHARMA TECHNOLOGY INC. (CN) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051387-A1 | WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | TP53, GOT1, PDCD2L | OGA 3278/4885CYP2D6 829/4885THRB 4561/4885 |
| US-20150011740-A1 | FLUORINE-CONTAINING WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | FOLR1, FOLR2, SLC46A1 | OGA 4132/4885CYP2D6 1022/4885THRB 4020/4885 |
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | FARS2, GOT2, HADHB | OGA 4839/4885CYP2D6 998/4885THRB 4746/4885 |
| US-20140349955-A1 | USE OF FLUORINE-CONTAINING WATER SOLUBLE PLATINUM COMPLEX IN PREPARING DRUGS FOR PREVENTION AND TREATMENT OF CANCERS | MCL1, BRCA1, FOLR1 | OGA 4332/4885CYP2D6 552/4885THRB 4191/4885 |
| US-20160256481-A1 | USE OF WATER SOLUBLE PLATINUM COMPLEX IN PREPARING DRUGS FOR PREVENTION AND TREATMENT OF CANCERS | BRCA1, MCL1, TP53 | OGA 4088/4885CYP2D6 552/4885THRB 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.