SCHEMBL1625977

SCHEMBL1625977

O=C1CCCCCN1c1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.51
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.45
P2RX7 Q99572 3/20 0.44
POLB P06746 2/20 0.44
SCN9A Q15858 1/20 0.43
HSD17B10 Q99714 2/20 0.42
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
CYP1A2 P05177 1/20 0.42
HTR1A P08908 1/20 0.42
CYP2D6 P10635 1/20 0.42
NCF1 P14598 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
HTR2A P28223 1/20 0.42
HTR7 P34969 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610033 0.98 DDAH1 (0.49) DDAH1MEN1KMT2AMAPTP2RX7
SCHEMBL29929651 0.93 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL29741442 0.93 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL611001 0.93 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL1626105 0.86 POLB (0.49) DDAH1MEN1KMT2AMAPTP2RX7
SCHEMBL14860996 0.81 CYP3A4 (0.44) MEN1KMT2ASCN9ACYP1A2HTR1A
SCHEMBL27555104 0.79 SCN9A (0.47) MEN1KMT2AMAPTSCN9AHSD17B10
SCHEMBL20103130 0.77 ADRA1A (0.48) MAPTP2RX7POLBHSD17B10CYP1A2
SCHEMBL718741 0.76 POLB (0.58) DDAH1MEN1KMT2AMAPTPOLB
SCHEMBL28834312 0.76 KEAP1 (0.53) MEN1KMT2AMAPTHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173200-A Bleaching compositions and bleach-additives comprising bleach activators effective at low perhydroxyl concentrations PROCTER & GAMBLE (US) 1998-02-11 CN claimed
CN-1173201-A Use of bleach activators for low perhydroxyl concentrations PROCTER & GAMBLE (US) 1998-02-11 CN claimed
EP-0792345-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP claimed
EP-0792343-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP claimed
US-5635104-A Bleaching solutions and method utilizing selected bleach activators effective at low perhydroxyl concentrations THE PROCTER & GAMBLE COMPANY (US) 1997-06-03 US claimed
WO-1996016155-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
WO-1996016156-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
EP-2004744-B1 COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2017-12-06 EP disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493629-B2 Modified butadiene-based polymer composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-11-15 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-5155161-A Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis NIPPON ZEON CO., LTD. (JP) 1992-10-13 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
EP-0382205-A2 Additive for thermosetting resins and thermosetting resin composition containing additive NIPPON ZEON CO., LTD. (JP) 1990-08-16 EP disclosed