SCHEMBL610033

SCHEMBL610033

O=C1CCCCN1c1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.49
MAPT P10636 2/20 0.46
P2RX7 Q99572 3/20 0.45
POLB P06746 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SCN9A Q15858 1/20 0.44
HSD17B10 Q99714 2/20 0.44
HTR1A P08908 2/20 0.44
HTR6 P50406 2/20 0.44
HTR3E A5X5Y0 1/20 0.44
HTR3B O95264 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
NCF1 P14598 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
HTR1D P28221 1/20 0.44
HTR1B P28222 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1625977 0.98 DDAH1 (0.51) DDAH1MAPTP2RX7POLBMEN1
SCHEMBL29929651 0.95 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL611001 0.95 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL29741442 0.95 SCN9A (0.47) DDAH1MAPTP2RX7POLBSCN9A
SCHEMBL1626105 0.88 POLB (0.49) DDAH1MAPTP2RX7POLBMEN1
SCHEMBL14860996 0.82 CYP3A4 (0.44) MEN1KMT2ASCN9AHTR1AHTR6
SCHEMBL27555104 0.81 SCN9A (0.47) MAPTMEN1KMT2ASCN9AHSD17B10
SCHEMBL718741 0.77 POLB (0.58) DDAH1MAPTPOLBMEN1KMT2A
SCHEMBL28834312 0.77 KEAP1 (0.53) MAPTMEN1KMT2AHSD17B10CYP1A2
SCHEMBL3984909 0.76 ADRA1B (0.45) MAPTPOLBMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
CN-105722909-B Pneumatic tire 住友橡胶工业株式会社 2018-04-06 CN disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
EP-2004744-B1 COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2017-12-06 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
CN-106749330-A A kind of Hete rocyclic derivatives and the organic luminescent device using the Hete rocyclic derivatives 长春海谱润斯科技有限公司 2017-05-31 CN disclosed
CN-103450515-B Rubber compound used for studless tire and studless tire 住友橡胶工业株式会社 2017-05-24 CN disclosed
US-5216080-A Butadiene-styrene copolymers endcapped with N-modified amino ketones, thioamino ketones, thioamino aldehydes, lactams, thiolactams, ethyleneurea and thioethylene urea; wear resistant, large-sized tires NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
US-5155161-A Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis NIPPON ZEON CO., LTD. (JP) 1992-10-13 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
US-5001196-A Process for preparation of diene type polymer rubber NIPPON ZEON CO., LTD. (JP) 1991-03-19 US disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
EP-0382205-A2 Additive for thermosetting resins and thermosetting resin composition containing additive NIPPON ZEON CO., LTD. (JP) 1990-08-16 EP disclosed
US-4328026-A PLANT GROWTH REGULATORS, ETHYLENE GENERATORS GAF CORPORATION (US) 1982-05-04 US disclosed