Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA6 | P23280 | 5/20 | 0.55 |
| ▸ | CA7 | P43166 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA4 | P22748 | 4/20 | 0.55 |
| ▸ | CA5A | P35218 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | CASP2 | P42575 | 2/20 | 0.55 |
| ▸ | F13A1 | P00488 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | THPO | P40225 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16260139 | 1.00 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL14522871 | 0.98 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19240898 | 0.93 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| SCHEMBL364371 | 0.90 | — | — | |
| SCHEMBL19086825 | 0.88 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL10636393 | 0.87 | UBE2N (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL25565749 | 0.87 | CYP2C19 (0.45) | CA12CA6CA7CA9CA14 | |
| SCHEMBL24001448 | 0.86 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL27105697 | 0.86 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21565017 | 0.86 | CA12 (0.43) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697693-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-07-11 | — | — | US | disclosed |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-13 | — | — | US | disclosed |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-06-08 | — | — | US | disclosed |
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-06-08 | — | — | US | disclosed |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210347918-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2021-11-11 | — | — | US | disclosed |
| US-20210346424-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-11-11 | — | — | US | disclosed |
| US-11026965-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2020-07-09 | — | — | US | disclosed |
| US-20190343869-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-11-14 | — | — | US | disclosed |
| WO-2019173539-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20190002429-A1 | Derivatives of Xanthone Compounds | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2019-01-03 | — | — | US | disclosed |
| US-20140349918-A1 | DERIVATIVES OF XANTHONE COMPOUNDS | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2014-11-27 | — | — | US | disclosed |
| US-20140349918-A1 | DERIVATIVES OF XANTHONE COMPOUNDS | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002429-A1 | Derivatives of Xanthone Compounds | XDH, XPA, SQLE | CA12 4592/4885CA6 3725/4885CA7 4122/4885 |
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | CA12 3584/4885CA6 1006/4885CA7 1735/4885 |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | CA12 3584/4885CA6 1006/4885CA7 1735/4885 |
| US-20190343869-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | CA12 3440/4885CA6 1791/4885CA7 1562/4885 |
| US-20210347918-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | CA12 4376/4885CA6 2338/4885CA7 1675/4885 |
| US-20140349918-A1 | DERIVATIVES OF XANTHONE COMPOUNDS | XDH, XPA, SQLE | CA12 4592/4885CA6 3725/4885CA7 4122/4885 |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | CA12 3440/4885CA6 1791/4885CA7 1562/4885 |
| US-11026965-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | CA12 3440/4885CA6 1791/4885CA7 1562/4885 |
| US-11697693-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | CA12 4376/4885CA6 2338/4885CA7 1675/4885 |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | NOS2, NOS3, NOS1 | CA12 3584/4885CA6 1006/4885CA7 1735/4885 |
| US-20210346424-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | CA12 3440/4885CA6 1791/4885CA7 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.