Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21873644 | 0.89 | CYP2A6 (0.39) | CYP1A2CYP2A6ACHEGABRA1GABRB2 | |
| SCHEMBL16260530 | 0.89 | RAPGEF4 (0.36) | RAPGEF4CYP1A2CYP2A6CA2ALDH1A1 | |
| SCHEMBL19058224 | 0.78 | CYP1A2 (0.41) | RAPGEF4CYP1A2CYP2A6ACHEFFAR4 | |
| SCHEMBL16263982 | 0.76 | RAPGEF4 (0.39) | RAPGEF4CYP1A2CYP2A6ACHEATM | |
| SCHEMBL2548312 | 0.70 | RAPGEF4 (0.36) | RAPGEF4CYP1A2CYP2A6CA2ALDH1A1 | |
| SCHEMBL21873451 | 0.70 | CYP2A6 (0.39) | CYP1A2CYP2A6ACHEGABRA1GABRB2 | |
| SCHEMBL29193803 | 0.67 | ACHE (0.50) | CYP1A2ACHEALDH1A1TSHR | |
| SCHEMBL26556085 | 0.66 | PDK2 (0.36) | RAPGEF4ALDH1A1 | |
| SCHEMBL5362839 | 0.64 | RAPGEF4 (0.39) | RAPGEF4CYP1A2CYP2A6FFAR4CA1 | |
| SCHEMBL11552812 | 0.64 | ACHE (0.45) | RAPGEF4CYP1A2CYP2A6ACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350303-A1 | CATALYSTS FOR THE PRODUCTION OF METHANOL FROM CARBON DIOXIDE | UNIVERSITé LAVAL (CA) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350303-A1 | CATALYSTS FOR THE PRODUCTION OF METHANOL FROM CARBON DIOXIDE | SCO2, MGLL, CAT | RAPGEF4 721/4885CYP1A2 783/4885CYP2A6 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.