SCHEMBL5362839

SCHEMBL5362839

Cc1cc(C)c(P(Cl)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 10/20 0.39
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30
GRIN2D O15399 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2884938 0.82 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL9329893 0.78 RAPGEF4 (0.42) RAPGEF4ALDH1A1FFAR4CA1CA2
SCHEMBL11785341 0.75 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL301709 0.75 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL31325570 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
Silver SCHEMBL31010581 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
Iodide SCHEMBL9662368 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
Bromide SCHEMBL3679642 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8029515 0.73 CYP2A6 (0.45) ALDH1A1CYP1A2CYP2A6TSHRTDP1
SCHEMBL8773546 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 US disclosed
CN-119998255-A Catalytic carboxycarbonylation of olefins to form anhydrides 北卡罗来纳大学教堂山分校 2025-05-13 CN disclosed
EP-4543841-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES The University of North Carolina at Chapel Hill (US) 2025-04-30 EP disclosed
WO-2025021733-A1 ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2-DIHYDROQUINOLINES IN THE PRESENCE OF A CHIRAL IRIDIUM (P,S)-LIGAND CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2025-01-30 WO disclosed
US-12107264-B2 Anode active material comprising metal phosphide coating on surface of carbon material, preparation method therefor, nonaqueous lithium secondary battery comprising anode active material, and manufacturing method therefor KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE (KR) 2024-10-01 US disclosed
WO-2023250180-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-12-28 WO disclosed
CN-111793087-B Luminescent material, delayed phosphor and organic light-emitting element 浙江虹舞科技有限公司 2023-06-09 CN disclosed
US-20220216462-A1 ANODE ACTIVE MATERIAL COMPRISING METAL PHOSPHIDE COATING ON SURFACE OF CARBON MATERIAL, PREPARATION METHOD THEREFOR, NONAQUEOUS LITHIUM SECONDARY BATTERY COMPRISING ANODE ACTIVE MATERIAL, AND MANUFACTURING METHOD THEREFOR KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE (KR) 2022-07-07 US disclosed
EP-3307748-B1 FRUSTRATED LEWIS PAIRS UNIV OXFORD INNOVATION LTD (GB) 2022-03-09 EP disclosed
CN-111793087-A Luminescent material, delayed phosphor and organic light-emitting element 浙江虹舞科技有限公司 2020-10-20 CN disclosed
US-7060768-B2 Polymerization of olefinic compounds E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-13 US disclosed
US-20050054854-A1 Method for the production of arylamines MERCK PATENT GMBH (DE) 2005-03-10 US disclosed
US-20040158012-A1 Polymerization of olefinic compounds BROOKHART MAURICE S (US) 2004-08-12 US disclosed
EP-1442007-A1 METHOD FOR THE PRODUCTION OF ARYLAMINES Covion Organic Semiconductors GmbH (DE) 2004-08-04 EP disclosed
US-6710007-B2 TRANSITION METAL COMPLEXES OF IMINES, AMINES OR PHOSPHINES CONTAINING ESTERS OR AMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-23 US disclosed
EP-1355956-A2 POLYMERIZATION OF OLEFINIC COMPOUNDS E.I. Dupont de Nemours and Company (US) 2003-10-29 EP disclosed
US-20030125485-A1 Polymerization of olefinic compounds NORTH CAROLINA AT CHAPEL HILL, UNIVERSITY OF 2003-07-03 US disclosed
WO-2003037844-A1 METHOD FOR THE PRODUCTION OF ARYLAMINES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-05-08 WO disclosed
WO-2002059165-A2 POLYMERIZATION OF OLEFINIC COMPOUNDS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2002-08-01 WO disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 RAPGEF4 860/4885ALDH1A1 688/4885KDM4E 500/4885
US-20050054854-A1 Method for the production of arylamines DDT, PDS5A, KMO RAPGEF4 3564/4885ALDH1A1 2177/4885KDM4E 1811/4885
US-20030125485-A1 Polymerization of olefinic compounds PORCN, PHOSPHO1, TEC RAPGEF4 1003/4885ALDH1A1 2253/4885KDM4E 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.