SCHEMBL16263231

SCHEMBL16263231

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nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGF1 P05230 2/20 0.31
FGF2 P09038 1/20 0.31
F10 P00742 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16263233 0.89 F10 (0.35) FGF1F10
SCHEMBL19677568 0.84 F10 (0.41) FGF1FGF2F10
SCHEMBL19677566 0.83 BDNF (0.38) F10
SCHEMBL16263232 0.83 F10 (0.33) FGF1F10
SCHEMBL16263230 0.81 AMY2A (0.34) FGF1F10
SCHEMBL19678405 0.80 F10 (0.33) FGF1FGF2F10
SCHEMBL19677572 0.76 F10 (0.43) FGF1FGF2F10
SCHEMBL19677573 0.72 AMY2A (0.35) F10
SCHEMBL14977885 0.69 F10 (0.33) F10
SCHEMBL19677570 0.69 LGALS3 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140349962-A1 RAPID TWO-STEP SYNTHESIS OF ANTI-COAGULANTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349962-A1 RAPID TWO-STEP SYNTHESIS OF ANTI-COAGULANTS HPSE, SERPINC1, HPN FGF1 2110/4885FGF2 841/4885F10 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.