Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732747 | 0.85 | HTT (0.40) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL16263362 | 0.82 | PLA2G2C (0.35) | HTTEPHX2PLA2G2C | |
| SCHEMBL22735038 | 0.80 | HTT (0.43) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL17736192 | 0.77 | THRB (0.40) | HTTALDH1A1THRBPLA2G2CTSHR | |
| SCHEMBL6730205 | 0.77 | ALDH1A1 (0.56) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL9936878 | 0.75 | HTT (0.43) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL17489563 | 0.75 | HTT (0.39) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL9936958 | 0.75 | HTT (0.39) | HTTALDH1A1THRBEPHX2PLA2G2C | |
| SCHEMBL1591167 | 0.74 | CA1 (0.35) | HTTALDH1A1EPHX2 | |
| SCHEMBL9936931 | 0.73 | NAAA (0.44) | HTTALDH1A1THRBEPHX2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | AFF4, AFF1, HAX1 | HTT 744/4885ALDH1A1 2153/4885THRB 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.