SCHEMBL1626467

SCHEMBL1626467

CCOC(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
HDAC4 P56524 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
ABCB11 O95342 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
HTR2A P28223 1/20 0.47
PMP22 Q01453 1/20 0.47
PPARA Q07869 1/20 0.47
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
GAA P10253 1/20 0.46
GPR119 Q8TDV5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11597794 0.85 LMNA (0.47) HDAC4HDAC7HDAC5L3MBTL1SMN1; SMN2
SCHEMBL1041533 0.85 MMP8 (0.51) CA12CA1CA2CA9L3MBTL1
SCHEMBL3541681 0.84 MEN1 (0.49) L3MBTL1SMN1; SMN2CYP1A2CYP3A4TSHR
SCHEMBL2798571 0.83 CA12 (0.48) CA12CA1CA2CA9L3MBTL1
SCHEMBL7796149 0.83 PSEN1 (0.50) CA12CA1CA2CA9L3MBTL1
SCHEMBL27537598 0.83 CA12 (0.48) CA12CA1CA2CA9L3MBTL1
SCHEMBL1395571 0.82 CA12 (0.55) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL11597064 0.82 SMN1; SMN2 (0.50) HDAC4HDAC7HDAC5L3MBTL1SMN1; SMN2
SCHEMBL4517176 0.81 L3MBTL1 (0.49) CA12CA1CA2CA9L3MBTL1
SCHEMBL5321055 0.81 CA12 (0.47) CA12CA1CA2CA9L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117604047-A Preparation method of high-purity DHA ethyl ester 华南理工大学 2024-02-27 CN claimed
US-4080207-A Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents EASTMAN KODAK COMPANY (US) 1978-03-21 US claimed
CN-115896191-B Preparation method of phospholipid DHA and microcapsule embedding method 润科生物工程(福建)有限公司 2026-02-27 CN disclosed
US-20260001877-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-01-01 US disclosed
EP-3763364-B1 SELF-EMULSIFYING COMPOSITION OF OMEGA-3 FATTY ACID MOCHIDA PHARM CO LTD (JP) 2025-11-05 EP disclosed
WO-2025090465-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-05-01 WO disclosed
WO-2025090480-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-05-01 WO disclosed
CN-119867010-A Egg rich in DHA nutrients and production method thereof 青岛藻源海洋生物科技有限公司 2025-04-25 CN disclosed
CN-119837197-A DHA nutrient for poultry, production method and application thereof 青岛藻源海洋生物科技有限公司 2025-04-18 CN disclosed
CN-115478084-B Preparation method of polyunsaturated fatty acid ester 嘉必优生物技术(武汉)股份有限公司 2025-02-07 CN disclosed
EP-4468884-A1 LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT Amarin Pharmaceuticals Ireland Limited (IE) 2024-12-04 EP disclosed
WO-2011115813-A1 LACTAM ACETAMIDES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2011-09-22 WO disclosed
US-7928139-B2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof AMGEN INC. (US) 2011-04-19 US disclosed
US-20100048572-A1 NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF AMGEN INC. (US) 2010-02-25 US disclosed
US-7635715-B2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof AMGEN INC. (US) 2009-12-22 US disclosed
EP-2111399-A2 NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF Amgen Inc. (US) 2009-10-28 EP disclosed
US-20090093483-A1 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof AMGEN INC. (US) 2009-04-09 US disclosed
WO-2008076427-A2 NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF AMGEN INC. (US) 2008-06-26 WO disclosed
US-5210160-A PREPARATION OF HOMOPOLYMERS OF ETHENE AND COPOLYMERS OF ETHENE WITH HIGHER A-MONOOLEFINS USING A ZIEGLER CATALYST SYSTEM BASF AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
US-4066785-A Esters of α-hydroperoxy-bis-p-halo-phenylacetic acids YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048572-A1 NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF EGLN2, EGLN3, HIF1AN CA12 2760/4885CA1 2235/4885CA2 1160/4885
US-20090093483-A1 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof EGLN2, EGLN3, HIF1AN CA12 2760/4885CA1 2235/4885CA2 1160/4885
US-20260001877-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN CNR1, SCN1B, OPRL1 CA12 1327/4885CA1 781/4885CA2 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.