Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566472 | 0.87 | MAPT (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11564285 | 0.87 | MAPT (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3279844 | 0.85 | KMT2A (0.47) | LMNAALDH1A1TDP1SMN1; SMN2TSHR | |
| SCHEMBL9438866 | 0.84 | SMN1; SMN2 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9232941 | 0.83 | ESR1 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL1792502 | 0.83 | ESR1 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL1626467 | 0.83 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL1041533 | 0.83 | MMP8 (0.51) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9235662 | 0.83 | ESR1 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28968063 | 0.83 | L3MBTL1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773656-A | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | claimed |
| JP-9051798-A | — | — | None | — | — | JP | disclosed |
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-09-26 | — | — | US | disclosed |
| EP-4273129-A1 | RORgammaT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143771-A1 | RORγT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-07-07 | — | — | WO | disclosed |
| CN-114685363-A | ROR gamma t regulator, preparation method and application thereof | 上海医药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-0759426-B1 | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AG (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-5773656-A | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0759426-A2 | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AG (DE) | 1997-02-26 | — | — | EP | disclosed |
| JP-H0951798-A | PRODUCTION OF OPTICALLY ACTIVE 1-ARYLALKYLAMINES | BAYER AG | 1997-02-25 | — | — | JP | disclosed |
| US-5451607-A | APPLYING HYDRAZONE DERIVATIVE TO A LOCUS TO CONTROL PESTS | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-09-19 | — | — | US | disclosed |
| CN-1078460-A | The method for making of hydrazone derivative and application | SUMITOMO CHEMICAL CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| EP-0567138-A2 | Hydrazone derivatives, process for producing the same, insecticides and/or acaricides containing the same as active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-3991201-A | 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317686-A1 | RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | RORC, RORB, RORA | PSEN1 2829/4885PSEN2 3244/4885APH1B 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.