Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.91 |
| ▸ | GLA | P06280 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 1/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.91 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | CA1 | P00915 | 15/20 | 0.59 |
| ▸ | CA2 | P00918 | 15/20 | 0.59 |
| ▸ | CA9 | Q16790 | 13/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451303 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390764 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283884 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390632 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| Lithium Ion SCHEMBL25256858 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23387500 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390647 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL25262176 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283888 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283886 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117837808-A | Preparation method of super-oleophilic oil-guiding cotton, atomization core and electronic cigarette | 品度生物科技(深圳)有限公司 | 2024-04-09 | — | — | CN | claimed |
| US-11476462-B2 | LiFePO4 precursor for manufacturing electrode material of Li-ion battery and method for manufacturing the same | NATIONAL TSING HUA UNIVERSITY (TW) | 2022-10-18 | — | — | US | claimed |
| EP-3752496-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2020-12-23 | — | — | EP | claimed |
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | claimed |
| WO-2019161280-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2019-08-22 | — | — | WO | claimed |
| CN-104403455-A | Safe, environment-friendly, heat-resisting and antibacterial water-based paint | ANHUI JINDUN PAINT CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-102978272-B | Novel phytosterol or/and phytostanol derivative preparation method | JIANGNAN UNIVERSITY (CN) | 2014-10-15 | — | — | CN | claimed |
| CN-102978272-A | Novel phytosterol or/and phytostanol derivative preparation method | UNIV JIANGNAN | 2013-03-20 | — | — | CN | claimed |
| CN-102321138-A | A kind of novel preparation method of fatty acid phytosterin ester | UNIV JIANGNAN | 2012-01-18 | — | — | CN | claimed |
| US-5723075-A | HEAT RESISTANT ABSORBERS WITH RESINS FOR SHIELDS | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-03-03 | — | — | US | claimed |
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4130504-A | COPPER COMPOUND, ANIONIC SURFACTANT, ALKALINE MATERIAL AS CATALYST | ICI AMERICAS INC. (US) | 1978-12-19 | — | — | US | claimed |
| US-4070383-A | COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM | ICI AMERICAS INC. (US) | 1978-01-24 | — | — | US | claimed |
| CN-116854630-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2025-03-27 | — | — | US | disclosed |
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |
| CN-1071420-A | 4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl] phenyl]-5-methyl-3H-1,2,4-triazole-3-ketone derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1993-04-28 | — | — | CN | disclosed |
| US-4130504-A | COPPER COMPOUND, ANIONIC SURFACTANT, ALKALINE MATERIAL AS CATALYST | ICI AMERICAS INC. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4070383-A | COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM | ICI AMERICAS INC. (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | CYP11A1, CYP11B1, CYP11B2 | RECQL 643/4885TSHR 3015/4885GLA 1126/4885 |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | RECQL 643/4885TSHR 3015/4885GLA 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.