SCHEMBL16266106

SCHEMBL16266106

O=CCc1nc(CO)c[nH]1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
PMP22 Q01453 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7757806 0.81 PKM (0.32) PKMKDM4EPOLBRECQLPMP22
SCHEMBL3099997 0.79
Urea SCHEMBL28454325 0.74 CCNC (0.31)
SCHEMBL674184 0.74
SCHEMBL15501205 0.72
SCHEMBL2512273 0.72
SCHEMBL14151769 0.71 BACE1 (0.30)
SCHEMBL8992520 0.71 ADORA3 (0.33)
Hydrochloric Acid SCHEMBL29950960 0.71 CCR1 (0.30)
SCHEMBL12489591 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2537831-B1 IMIDAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2014-12-03 EP claimed
EP-4017844-A1 COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER AC BioScience SA (CH) 2022-06-29 EP disclosed
WO-2021032857-A1 COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER AC BIOSCIENCE SA (CH) 2021-02-25 WO disclosed
EP-2537831-B1 IMIDAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2014-12-03 EP disclosed