Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 10/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328962 | 0.86 | TACR1 (0.53) | KMT2AGAATACR1KDM1AMAOA | |
| SCHEMBL8328961 | 0.86 | TACR1 (0.53) | KMT2AGAATACR1KDM1AMAOA | |
| SCHEMBL8681005 | 0.82 | TACR1 (0.39) | KMT2AGAATACR1KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL8681079 | 0.81 | TACR1 (0.39) | KMT2AGAATACR1KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL9420087 | 0.81 | TACR1 (0.57) | TACR1 | |
| SCHEMBL20178136 | 0.81 | TACR1 (0.55) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL20178205 | 0.80 | TACR1 (0.46) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL8701388 | 0.80 | TACR1 (0.58) | KMT2AGAATACR1TDP1 | |
| SCHEMBL8658284 | 0.80 | MAPT (0.41) | KMT2ATACR1SMN1; SMN2MEN1POLB | |
| SCHEMBL8706700 | 0.79 | SLC6A2 (0.45) | KMT2ATACR1SMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110093959-A1 | CRYPTOTIS PARVA SCREENING MODEL FOR ANTIEMETIC POTENTIAL | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2011-04-21 | — | — | US | disclosed |
| WO-2009097495-A1 | THE CRYPTOTIS PARVA SCREENING MODEL FOR ANTIEMETIC POTENTIAL | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-0861235-A1 | SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS | PFIZER INC. (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997008144-A1 | SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS | PFIZER PHARMACEUTICALS INC. (JP) | 1997-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110093959-A1 | CRYPTOTIS PARVA SCREENING MODEL FOR ANTIEMETIC POTENTIAL | PNMT, SLC1A2, SLC1A1 | KMT2A 264/4885GAA 4012/4885TACR1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.