SCHEMBL162704

SCHEMBL162704

CC1C(=O)N(C)C(=O)N1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.41
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
PABPC1 P11940 1/20 0.37
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
ADORA3 P0DMS8 4/20 0.34
ADORA2A P29274 4/20 0.34
ADORA1 P30542 3/20 0.34
MAPK1 P28482 1/20 0.32
BRD4 O60885 1/20 0.31
KDM4A O75164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11918894 1.00 ADRA2C (0.41) ADRA2CKMT2AMEN1PABPC1ALDH1A1
SCHEMBL361227 0.76 ADRA2C (0.39) ADRA2CKMT2AMEN1PABPC1ALDH1A1
SCHEMBL8826943 0.76 ADRA2C (0.42) ADRA2CKMT2AMEN1PABPC1MAPK1
SCHEMBL13391600 0.76 ADRA2C (0.42) ADRA2CKMT2AMEN1PABPC1MAPK1
SCHEMBL5711438 0.75 ADRA2C (0.35) ADRA2CKMT2AMEN1PABPC1
SCHEMBL23941234 0.74 ADRA2C (0.38) ADRA2CKMT2AMEN1PABPC1MAPK1
SCHEMBL361225 0.74 ALDH1A1 (0.36) ADRA2CKMT2AMEN1PABPC1ALDH1A1
SCHEMBL631042 0.74 ALDH1A1 (0.32) ADRA2CKMT2AMEN1PABPC1ALDH1A1
SCHEMBL12806567 0.74 ADRA2C (0.38) ADRA2CKMT2AMEN1PABPC1MAPK1
SCHEMBL13979791 0.74 ALDH1A1 (0.32) ADRA2CKMT2AMEN1PABPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116288929-A Preparation method of polyurethane nanofiber membrane 浙江技立新材料股份有限公司 2023-06-23 CN claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-20100029689-A1 PHOSPHODIESTERASE 4 INHIBITORS MEMORY PHARMACEUTICALS CORPORATION (US) 2010-02-04 US claimed
WO-2010003084-A2 PHOSPHODIESTERASE 4 INHIBITORS MEMORY PHARMACEUTICALS CORPORATION (US) 2010-01-07 WO claimed
EP-0571903-B1 A method for preparing low free formaldehyde methylol-hydantoins and compositions thereof LONZA AG (US) 1996-08-28 EP claimed
CN-114657611-B Alkaline copper electroplating solution and electroplating method thereof 佛山市诺诚科技有限公司 2024-03-12 CN disclosed
US-11739239-B2 Thermally crosslinkable composition SUNSTAR ENGINEERING INC. (JP) 2023-08-29 US disclosed
CN-116323045-A Silver powder, method for producing same, and conductive resin composition 三井金属矿业株式会社 2023-06-23 CN disclosed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
CN-107603357-B Coating material for forming conductive release layer, method for producing same, conductive release film, and method for producing same 信越聚合物株式会社 2020-10-16 CN disclosed
US-20200115505-A1 POLYMERIZED IN-SITU HYBRID SOLID ION-CONDUCTIVE COMPOSITIONS Blue Current, Inc. 2020-04-16 US disclosed
CN-109071487-A PROCESS FOR THE PREPARATION OF HERBICIDAL COMPOUNDS 先正达参股股份有限公司 2018-12-21 CN disclosed
WO-1999006361-A2 N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES ABBOTT LABORATORIES (US) 1999-02-11 WO disclosed
EP-0839339-A1 PHOTOGRAPHIC SYSTEM POLAROID CORPORATION (US) 1998-05-06 EP disclosed
EP-0816341-A1 Process for the preparation of chiral succinic acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-01-07 EP disclosed
WO-1997043691-A1 PHOTOGRAPHIC SYSTEM POLAROID CORPORATION (US) 1997-11-20 WO disclosed
EP-0144990-B1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-25 EP disclosed
US-4665017-A GRAIN GROWTH PROMOTOR AND INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
EP-0144990-A2 Process for preparing silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ADRA2C 4563/4885KMT2A 1080/4885MEN1 2213/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ADRA2C 4579/4885KMT2A 999/4885MEN1 2164/4885
US-20100029689-A1 PHOSPHODIESTERASE 4 INHIBITORS PDE4A, PDE4B, PDE3B ADRA2C 95/4885KMT2A 1324/4885MEN1 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.