Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DDT | P30046 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 4/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262453 | 0.93 | HNF4A (0.50) | DHODHKMOHNF4AKDM4EPTPN1 | |
| SCHEMBL29082654 | 0.85 | KMO (0.50) | DHODHKMOHNF4AKDM4ERXRA | |
| SCHEMBL15569353 | 0.84 | DHODH (0.58) | DHODHKMOHNF4ARXRARXRB | |
| SCHEMBL16271134 | 0.80 | TTR (0.49) | KMOHNF4AKDM4EPTPN1TTR | |
| SCHEMBL16271127 | 0.79 | TTR (0.47) | KMOHNF4AKDM4EPTPN1TTR | |
| SCHEMBL16271124 | 0.79 | CA2 (0.40) | DHODHKMOHNF4AKDM4ERXRA | |
| SCHEMBL28910860 | 0.78 | DHODH (0.50) | DHODHKMOHNF4ADDTFOLH1 | |
| SCHEMBL27893408 | 0.78 | DDT (0.57) | DHODHKMOHNF4APTPN1DDT | |
| SCHEMBL27588778 | 0.77 | TTR (0.53) | DHODHKMOHNF4AKDM4ETTR | |
| SCHEMBL28457215 | 0.77 | TPMT (0.46) | DHODHKMOKDM4ERXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114223041-A | Polymer functionalized magnetic particle embodiments for solute separation and devices and systems using the same | 巴特尔纪念研究院 | 2022-03-22 | — | — | CN | disclosed |
| US-9329154-B1 | Devices and methods to detect and quantify trace gases | SANDIA CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| CN-105026854-A | Adsorption systems using metal-organic frameworks | ARKEMA INC | 2015-11-04 | — | — | CN | disclosed |
| US-8904850-B1 | Materials, methods and devices to detect and quantify water vapor concentrations in an atmosphere | SANDIA CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |