SCHEMBL162734

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL162790	0.84	NPC1 (0.39)	RAB9ASMN1; SMN2NPC1TP53ALDH1A1
	SCHEMBL162165	0.78	CNR1 (0.39)	RAB9ASMN1; SMN2KMT2AALDH1A1L3MBTL1
	SCHEMBL163840	0.77	RAB9A (0.47)	RAB9ASMN1; SMN2NPC1TP53HSD17B10
	SCHEMBL164646	0.76	ANO1 (0.51)	RAB9ASMN1; SMN2MAPK1NPC1TP53
	SCHEMBL164703	0.75	BAZ2B (0.41)	RAB9ANPC1TP53HSD17B10PKM
	SCHEMBL163643	0.75	POLB (0.43)	RAB9ASMN1; SMN2NPC1TP53ALDH1A1
	SCHEMBL163851	0.72	ALOX15 (0.39)	SMN1; SMN2HSD17B10ALDH1A1TSHRL3MBTL1
	SCHEMBL164699	0.72	RAB9A (0.58)	RAB9ASMN1; SMN2MAPK1NPC1TP53
	SCHEMBL165757	0.71	CNR2 (0.37)	RAB9ASMN1; SMN2NPC1TP53HSD17B10
	SCHEMBL162922	0.71	KMT2A (0.43)	RAB9ASMN1; SMN2MAPK1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.