SCHEMBL162736

SCHEMBL162736

O=C(O)C(C(=O)O)c1ccsc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
DAO P14920 1/20 0.46
ALOX5 P09917 1/20 0.46
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
PTGS1 P23219 1/20 0.42
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
SLC1A3 P43003 2/20 0.39
SLC1A2 P43004 2/20 0.39
SLC1A1 P43005 2/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
HDAC1 Q13547 1/20 0.38
HPGD P15428 1/20 0.36
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11244144 0.98 SRC (0.48) SRCLCKFYNDAOALOX5
SCHEMBL10918696 0.98 SRC (0.48) SRCLCKFYNDAOALOX5
SCHEMBL9814548 0.90 ALOX5 (0.50) SRCLCKFYNDAOALOX5
SCHEMBL9814555 0.88 ALOX5 (0.41) SRCLCKFYNDAOALOX5
SCHEMBL10918695 0.86 SMN1; SMN2 (0.42) SRCLCKFYNDAOALOX5
SCHEMBL18734632 0.82 CYP2D6 (0.50) SRCLCKFYNDAOALOX5
SCHEMBL11260231 0.80 LMNA (0.41) SRCLCKFYNDAOALOX5
SCHEMBL200194 0.80 LMNA (0.52) LCKFYNDAOALOX5CES2
SCHEMBL9329422 0.80 LMNA (0.52) LCKFYNDAOALOX5CES2
SCHEMBL10969158 0.80 ALOX5 (0.44) LCKFYNDAOALOX5CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-119463390-A Nanocomposite dispersion liquid and preparation method thereof, and kit and method for detecting m6A-RNA and m5C-RNA 中国人民解放军陆军军医大学 2025-02-18 CN claimed
CN-117209330-B Special intelligent controlled-release fertilizer for corn and preparation method thereof 山东农业大学 2025-02-07 CN claimed
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN claimed
US-20240276856-A1 PREPARATION METHOD OF LIGHT-EMITTING DEVICE, LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS Beijing Boe Technology Development Co., Ltd. (CN) 2024-08-15 US claimed
CN-117209330-A Special intelligent controlled-release fertilizer for corn and preparation method thereof 山东农业大学 2023-12-12 CN claimed
CN-116649008-A Preparation method of light-emitting device, light-emitting device and light-emitting device 京东方科技集团股份有限公司 2023-08-25 CN claimed
CN-116554209-A A series of five-coordination copper complex crystal materials, and preparation method and application thereof 天津理工大学 2023-08-08 CN claimed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO claimed
CN-115616050-B Preparation method and application of vanadium battery electrolyte ion concentration sensor material 杭州德海艾科能源科技有限公司 2023-04-07 CN claimed
EP-0506687-A1 PROCESS FOR THE PRODUCTION OF 3-THIENYL MALONIC ACID DIALKYL ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-07 EP claimed
WO-1991009854-A1 PROCESS FOR THE PRODUCTION OF 3-THIENYL MALONIC ACID DIALKYL ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-11 WO claimed
US-4691029-A Process for producing 3-thienylmalonic acid BEECHAM GROUP P.L.C. (GB) 1987-09-01 US claimed
EP-0021644-B1 A SALT OF 3-THIENYLMALONIC ACID AND A PROCESS FOR THE PREPARATION OF 3-THIENYLMALONIC ACID BEECHAM GROUP PLC (GB) 1986-09-03 EP claimed
EP-0002846-B1 3-THIENYLMALONIC ACIDS, THE CORRESPONDING DIESTERS AND THEIR PREPARATION Océ-Andeno B.V. (NL) 1984-05-23 EP claimed
EP-0021645-B1 PROCESS FOR THE PREPARATION OF 3-THIENYLMALONIC ACID BEECHAM GROUP PLC (GB) 1983-08-17 EP claimed
US-4262129-A Preparation of a 3-thienylmalonic acid and the corresponding diesters OCE-ANDENO B.V. (NL) 1981-04-14 US claimed
EP-0021644-A1 A salt of 3-thienylmalonic acid and a process for the preparation of 3-thienylmalonic acid BEECHAM GROUP PLC (GB) 1981-01-07 EP claimed
EP-0021645-A1 Process for the preparation of 3-thienylmalonic acid BEECHAM GROUP PLC (GB) 1981-01-07 EP claimed
EP-0002846-A1 3-Thienylmalonic acids, the corresponding diesters and their preparation Océ-Andeno B.V. (NL) 1979-07-11 EP claimed