SCHEMBL16273617

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15659408	0.90	ALDH1A1 (0.50)	RORCALDH1A1MEN1KMT2AKDM4E
	SCHEMBL3928441	0.87	ALDH1A1 (0.51)	RORCALDH1A1MEN1KMT2ATSHR
	SCHEMBL16273683	0.86	ALDH1A1 (0.49)	ALDH1A1MEN1KMT2AKDM4ETSHR
	SCHEMBL3189296	0.85	ALDH1A1 (0.61)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL31299787	0.82	KDM4E (0.51)	ALDH1A1MEN1KMT2AKDM4ETSHR
	SCHEMBL1348885	0.82	KDM4E (0.51)	ALDH1A1MEN1KMT2AKDM4ETSHR
	SCHEMBL17420787	0.81	ALDH1A1 (0.48)	RORCALDH1A1MEN1KMT2ATSHR
	SCHEMBL9471937	0.79	HSP90AA1 (0.51)	ALDH1A1MEN1KMT2AKDM4ETSHR
	SCHEMBL1437391	0.78	MEN1 (0.48)	ALDH1A1MEN1KMT2AKDM4ETSHR
	SCHEMBL9472037	0.78	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2AKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.