SCHEMBL16273699

SCHEMBL16273699

CCc1cc(O)ccc1OCc1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
ELANE P08246 4/20 0.40
F2 P00734 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CTSG P08311 1/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
ATM Q13315 1/20 0.38
PLEC Q15149 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616638 0.85 L3MBTL1 (0.50) SLC6A4ALDH1A1L3MBTL1MAPTGAA
SCHEMBL19987598 0.83 CDK4 (0.48) KMT2AELANEF2ALDH1A1L3MBTL1
SCHEMBL16273692 0.83 FFAR4 (0.43) SLC6A2SLC6A4SLC6A3RECQL
SCHEMBL16273709 0.80 F2 (0.40) KMT2AF2ALDH1A1MAPTMEN1
SCHEMBL16273696 0.80 MRGPRX4 (0.49) MAPTGAATHRBFNTAFNTB
SCHEMBL1894477 0.80 ELANE (0.58) KMT2AELANEF2SLC6A2SLC6A3
SCHEMBL16273659 0.79 MRGPRX4 (0.59) ELANEF2ALDH1A1KDM4E
SCHEMBL16273708 0.77 MRGPRX4 (0.44) KMT2AALDH1A1MAPTMEN1NPSR1
SCHEMBL19987538 0.77 PTGDR2 (0.41) KMT2AELANEF2CTSGALDH1A1
SCHEMBL16273690 0.77 MAOB (0.52) KMT2AALDH1A1L3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029030-B1 TETRAZOLINONE COMPOUND, AND USE THEREFOR SUMITOMO CHEMICAL CO (JP) 2019-09-04 EP disclosed
EP-3006440-B1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME SUMITOMO CHEMICAL CO (JP) 2018-03-21 EP disclosed
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
EP-3029030-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2016-06-08 EP disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 EP disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed