Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCND1 | P24385 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831472 | 0.85 | CDK4 (0.48) | CDK4CCND1MAOBSLC1A5ALDH1A1 | |
| SCHEMBL16273699 | 0.83 | KMT2A (0.40) | ALDH1A1GAAMAPTTHRBKDM4E | |
| SCHEMBL1894477 | 0.81 | ELANE (0.58) | ALDH1A1GAAMAPTRAB9ATHRB | |
| SCHEMBL19237543 | 0.81 | CDK4 (0.45) | CDK4CCND1MAOBSLC1A5ALDH1A1 | |
| SCHEMBL16273659 | 0.81 | MRGPRX4 (0.59) | ALDH1A1KDM4EF2ELANE | |
| SCHEMBL19322281 | 0.79 | RAB9A (0.44) | CDK4CCND1MAOBALDH1A1GAA | |
| SCHEMBL16273690 | 0.79 | MAOB (0.52) | MAOBALDH1A1GAAMAPTRAB9A | |
| SCHEMBL19987538 | 0.79 | PTGDR2 (0.41) | ALDH1A1GAAMAPTTHRBPTGDR2 | |
| SCHEMBL13567696 | 0.78 | MAPT (0.47) | ALDH1A1GAAMAPTRAB9ATHRB | |
| SCHEMBL16273629 | 0.77 | GABRA1 (0.40) | ALDH1A1GAAMAPTTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |