SCHEMBL16273668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16273743	0.86	POLB (0.39)	ESR2ARPOLBESR1PIK3CD
	SCHEMBL16273655	0.79	S1PR1 (0.46)	—
	SCHEMBL16273687	0.78	ESR2 (0.41)	ESR2ARPOLBESR1PIK3CD
	SCHEMBL16911501	0.72	HPGD (0.40)	ESR2ARESR1PIK3CDABL1
	SCHEMBL16911310	0.72	ESR2 (0.43)	ESR2ARESR1ADORA2AADORA1
	SCHEMBL16627170	0.71	ESR2 (0.45)	ESR2ARESR1PIK3CDABL1
	SCHEMBL16911354	0.70	ESR2 (0.36)	ESR2ARESR1PIK3CDABL1
	SCHEMBL16273666	0.70	SRC (0.39)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL17290267	0.69	PTGS2 (0.35)	ARPOLBPIK3CDABL1EGFR
	SCHEMBL16627204	0.67	ESR2 (0.42)	ESR2ARESR1PIK3CDABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.