SCHEMBL16273696

SCHEMBL16273696

Nc1ccccc1COc1ccc(O)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 8/20 0.49
MAPT P10636 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TP53 P04637 1/20 0.43
HTT P42858 1/20 0.43
GAA P10253 1/20 0.43
THRB P10828 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
DCPS Q96C86 1/20 0.40
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616592 0.83 L3MBTL1 (0.51) MRGPRX4MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL17677501 0.83 MRGPRX4 (0.48) MRGPRX4MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL28339206 0.82 TP53 (0.57) MAPTNPC1RAB9ASMN1; SMN2TP53
SCHEMBL16273692 0.81 FFAR4 (0.43) MRGPRX4FFAR4
SCHEMBL16273709 0.81 F2 (0.40) MAPTNPC1RAB9ASMN1; SMN2HTT
SCHEMBL19646121 0.80 MRGPRX4 (0.46) MRGPRX4
SCHEMBL18831630 0.80 MET (0.51) MRGPRX4MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16273699 0.80 KMT2A (0.40) MAPTGAATHRBFNTAFNTB
SCHEMBL16273702 0.80 MRGPRX4 (0.42) MRGPRX4MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16273708 0.79 MRGPRX4 (0.44) MRGPRX4MAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
EP-3029030-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2016-06-08 EP disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 EP disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed