Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.37 |
| ▸ | NMT1 | P30419 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.36 | |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26423089 | 0.97 | NMT2 (0.40) | FAPCALCRLCTSLFURINNMT2 | |
| SCHEMBL26295409 | 0.93 | FAP (0.36) | FAPFURINNMT2NMT1HDAC3 | |
| SCHEMBL3244447 | 0.91 | FAP (0.44) | FAPFURINNMT2NMT1ROCK2 | |
| SCHEMBL21416485 | 0.91 | FAP (0.44) | FAPFURINNMT2NMT1ROCK2 | |
| SCHEMBL15246622 | 0.91 | FAP (0.44) | FAPFURINNMT2NMT1ROCK2 | |
| SCHEMBL16266184 | 0.91 | FAP (0.44) | FAPFURINNMT2NMT1ROCK2 | |
| SCHEMBL24129094 | 0.90 | FAP (0.38) | FAPCTSLFURINNMT2NMT1 | |
| SCHEMBL24848129 | 0.90 | FAP (0.44) | FAPFURINHDAC3HDAC1HDAC2 | |
| SCHEMBL15686242 | 0.89 | NMT2 (0.45) | CALCRLCTSLFURINNMT2NMT1 | |
| SCHEMBL23286101 | 0.87 | FAP (0.42) | FAPFURINHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | MABPLEX INTERNATIONAL, LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20210230218-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | MABPLEX INTERNATIONAL, LTD. (CN) | 2021-07-29 | — | — | US | disclosed |
| EP-3838913-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | MabPlex International Co., Ltd. (CN) | 2021-06-23 | — | — | EP | disclosed |
| WO-2021077317-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | 烟台迈百瑞国际生物医药股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC | 2017-10-26 | — | — | US | disclosed |
| WO-2017176648-A1 | TOPOISOMERASE POISONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-10-12 | — | — | WO | disclosed |
| WO-2014193722-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2014-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | SHBG, PTMS, VIP | FAP 290/4885CALCRL 1602/4885CTSL 919/4885 |
| US-20230128167-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | VIP, DNPEP, PREP | FAP 70/4885CALCRL 1300/4885CTSL 1005/4885 |
| US-20210230218-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | VIP, DNPEP, PREP | FAP 70/4885CALCRL 1300/4885CTSL 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.