Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.37 |
| ▸ | PGR | P06401 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974806 | 0.90 | GABRA1 (0.47) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL18019197 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1MEN1LMNA | |
| SCHEMBL23387416 | 0.73 | GABRA1 (0.53) | GABRA1GABRB2NR3C1NR3C2PGR | |
| SCHEMBL38650833 | 0.73 | GABRA1 (0.53) | GABRA1GABRB2NR3C1NR3C2PGR | |
| SCHEMBL15492968 | 0.72 | GABRA1 (0.41) | GABRA1GABRB2NR3C1NR3C2PGR | |
| SCHEMBL10618777 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Dimethylamine SCHEMBL7033752 | 0.69 | SHBG (0.50) | GABRA1GABRB2NR3C1NR3C2PGR | |
| SCHEMBL2859454 | 0.69 | NR3C1 (0.36) | FABP3FABP4FABP5NR3C1NR3C2 | |
| SCHEMBL16248322 | 0.68 | BCL2 (0.39) | GABRA1GABRB2FABP3FABP4FABP5 | |
| SCHEMBL18878384 | 0.68 | FFAR1 (0.42) | GABRA1GABRB2ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014194250-A2 | NOVEL NANOCARRIER DELIVERED CANCER CHEMOTHERAPEUTIC AGENTS | UNIVERSITY OF CINCINNATI (US) | 2014-12-04 | — | — | WO | disclosed |