SCHEMBL16276409

SCHEMBL16276409

CCOC(=O)c1cnn(-c2cccnc2)c1N

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.77
HPGD P15428 3/20 0.77
RAB9A P51151 3/20 0.69
HTT P42858 1/20 0.69
TSHR P16473 4/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
NPC1 O15118 3/20 0.63
TP53 P04637 2/20 0.63
MAPT P10636 6/20 0.61
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30546669 1.00 ALDH1A1 (0.77) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL1143334 0.87 ALDH1A1 (1.00) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL3599042 0.86 ALDH1A1 (0.78) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL30546563 0.85 ALDH1A1 (0.55) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL31588026 0.85 ALDH1A1 (0.55) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL26123945 0.85 ALDH1A1 (0.55) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL16276410 0.84 RAB9A (0.71) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL31021624 0.84 RAB9A (0.70) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL16276328 0.84 RAB9A (0.70) ALDH1A1HPGDRAB9AHTTTSHR
SCHEMBL30254074 0.83 ALDH1A1 (0.53) ALDH1A1HPGDRAB9AHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4707276-A2 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2026-03-11 EP disclosed
EP-4499611-B1 MALT1 MODULATORS AND USES THEREOF RAREFIED BIOSCIENCES INC (US) 2026-02-18 EP disclosed
US-20250326738-A1 MALT1 Modulators and Uses Thereof RAREFIED BIOSCIENCES, INC. (US) 2025-10-23 US disclosed
EP-4499611-A1 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2025-02-05 EP disclosed
WO-2023192506-A1 MALT1 MODULATORS AND USES THEREOF RARIFIED BIOSCIENCES, INC. (US) 2023-10-05 WO disclosed
EP-3116868-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2018-06-06 EP disclosed
EP-3116868-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2018-06-06 EP disclosed
US-9920059-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-20 US disclosed
US-9920059-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-20 US disclosed
US-9920059-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-20 US disclosed
US-9688681-B2 Heterocyclic compounds as pest control agents BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
US-9688681-B2 Heterocyclic compounds as pest control agents BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
US-9688681-B2 Heterocyclic compounds as pest control agents BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
EP-3003042-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2017-06-21 EP disclosed
EP-3003042-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2017-06-21 EP disclosed
US-20160122353-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-05 US disclosed
US-20160122353-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-05 US disclosed
US-20160122353-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-05 US disclosed
WO-2015135843-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2015-09-17 WO disclosed
WO-2014191301-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2014-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122353-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, NISCH, ACHE ALDH1A1 2915/4885HPGD 612/4885RAB9A 462/4885
US-20250326738-A1 MALT1 Modulators and Uses Thereof MALT1, SQSTM1, PPP1R10 ALDH1A1 3447/4885HPGD 3460/4885RAB9A 1099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.