Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426394 | 0.87 | HSD11B1 (0.36) | NAAAHSD11B1ACSS2NR1I2USP1 | |
| SCHEMBL10281169 | 0.82 | USP1 (0.42) | ACSS2USP1 | |
| SCHEMBL9952255 | 0.80 | ALOX5AP (0.36) | NAAAHSD11B1ACSS2COMTNR1I2 | |
| SCHEMBL15412773 | 0.77 | BRD4 (0.40) | NAAAHSD11B1NR1I2USP1KDM4E | |
| SCHEMBL15412419 | 0.75 | ALOX5AP (0.36) | NAAAHSD11B1ACSS2NR1I2USP1 | |
| SCHEMBL15412733 | 0.75 | AKT1 (0.39) | NAAAHSD11B1NR1I2USP1KDM4E | |
| SCHEMBL10280731 | 0.74 | HSD11B1 (0.38) | HSD11B1ACSS2NR1I2USP1ATR | |
| SCHEMBL15412482 | 0.74 | USP30 (0.40) | HSD11B1NR1I2USP1ALDH1A1GAA | |
| SCHEMBL15426342 | 0.73 | NLRP3 (0.45) | ACSS2NR1I2KDM4EALDH1A1HPGD | |
| SCHEMBL15426433 | 0.73 | ALOX5AP (0.35) | NAAAHSD11B1ACSS2NR1I2USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278983-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364444-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR4A1, NR2C2, NR0B1 | NAAA 451/4885HSD11B1 1639/4885ACSS2 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.