Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17872144 | 0.92 | CA3 (0.38) | PAOXCA12CA2CA3CA4 | |
| SCHEMBL1519900 | 0.92 | — | — | |
| SCHEMBL25358087 | 0.90 | PAOX (0.37) | PAOXCA12CA2CA3CA4 | |
| SCHEMBL25350443 | 0.90 | PAOX (0.37) | PAOXCA12CA2CA3CA4 | |
| SCHEMBL6825158 | 0.90 | EPHX2 (0.37) | ALDH1A1ALDH1A2ALDH2ALDH1A3PRMT1 | |
| SCHEMBL11082957 | 0.88 | ALDH1A1 (0.40) | ALDH1A1ALDH1A2ALDH2ALDH1A3PRMT1 | |
| Hydrochloric Acid SCHEMBL11445365 | 0.86 | ALDH1A1 (0.39) | ALDH1A1ALDH1A2ALDH2ALDH1A3PRMT1 | |
| SCHEMBL23069642 | 0.82 | CA12 (0.50) | PAOXCA12CA2CA3CA4 | |
| SCHEMBL25351644 | 0.81 | CA12 (0.35) | PAOXCA12CA2CA3CA4 | |
| SCHEMBL18338812 | 0.80 | CA3 (0.54) | PAOXCA12CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364454-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364454-A1 | METAL-CHELATING COMPOUNDS HAVING AT LEAST ONE POLYAMINO CHAIN | SLC30A7, HAMP, SLC8B1 | PAOX 1033/4885CA12 2049/4885CA2 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.