Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21407621 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNAGAAPKMTSHR | |
| SCHEMBL8658630 | 0.79 | OR51E2 (0.43) | ALDH1A1LMNAGAAPKMTDP1 | |
| SCHEMBL6702996 | 0.79 | LMNA (0.40) | ALDH1A1LMNAKISS1RTDP1 | |
| SCHEMBL805277 | 0.77 | — | — | |
| SCHEMBL107741 | 0.77 | — | — | |
| SCHEMBL7712935 | 0.77 | — | — | |
| SCHEMBL16280863 | 0.77 | TSHR (0.36) | ALDH1A1TSHRKISS1RTDP1 | |
| SCHEMBL1781897 | 0.77 | TSHR (0.36) | ALDH1A1TSHRKISS1RTDP1 | |
| SCHEMBL14753893 | 0.77 | GABRR1 (0.42) | LMNATSHRKISS1R | |
| SCHEMBL17347612 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906868-B2 | Aminoglycoside derivatives | REMPEX PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |