Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599830 | 0.79 | KISS1R (0.50) | LMNAALDH1A1OR51E2THRBKISS1R | |
| SCHEMBL16280856 | 0.79 | ALDH1A1 (0.34) | LMNAALDH1A1KISS1RTDP1 | |
| SCHEMBL21407621 | 0.79 | ALDH1A1 (0.34) | LMNAALDH1A1KISS1RTDP1 | |
| SCHEMBL13113138 | 0.77 | — | — | |
| SCHEMBL13113139 | 0.77 | — | — | |
| SCHEMBL1926067 | 0.77 | — | — | |
| SCHEMBL14753893 | 0.77 | GABRR1 (0.42) | LMNAKISS1R | |
| SCHEMBL6699946 | 0.77 | THRB (0.43) | LMNAALDH1A1OR51E2THRBTDP1 | |
| SCHEMBL28163698 | 0.77 | PTPN1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6839516 | 0.76 | OR51E2 (0.60) | LMNAALDH1A1OR51E2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040146535-A1 | Agent for improving tissue penetration | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSHAFTEN E.V. (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040146535-A1 | Agent for improving tissue penetration | PGF, MMP8, MMP1 | LMNA 1714/4885ALDH1A1 1823/4885OR51E2 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.