Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628824 | 1.00 | SIRT2 (0.39) | SIRT2 | |
| SCHEMBL5030851 | 0.89 | FAAH (0.40) | — | |
| SCHEMBL2505666 | 0.78 | — | — | |
| SCHEMBL18396407 | 0.77 | SIRT2 (0.40) | SIRT2 | |
| Formaldehyde SCHEMBL9286356 | 0.73 | CPT1A (0.33) | — | |
| SCHEMBL5140463 | 0.71 | SIRT2 (0.46) | SIRT2 | |
| SCHEMBL2411591 | 0.70 | TSHR (0.42) | SIRT2 | |
| SCHEMBL11625298 | 0.70 | TSHR (0.42) | SIRT2 | |
| SCHEMBL1994954 | 0.70 | TSHR (0.42) | SIRT2 | |
| SCHEMBL12586891 | 0.70 | TSHR (0.42) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505139-B2 | THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME | SHISEIDO CO LTD (JP) | 2014-06-18 | — | — | EP | disclosed |
| EP-1505139-B1 | THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME | SHISEIDO CO LTD (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20110098231-A1 | Skin Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| US-7927615-B2 | Thickener, cosmetic preparation containing the same, and process for producing the same | SHISEIDO COMPANY, LTD. (JP) | 2011-04-19 | — | — | US | disclosed |
| EP-1387660-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-07-14 | — | — | EP | disclosed |
| EP-2168568-A1 | SKIN COSMETIC | Shiseido Company, Limited (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-20100029787-A1 | Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same | SHISEIDO COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20090258964-A1 | Skin Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| EP-1387660-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2006-05-17 | — | — | EP | disclosed |
| CN-1711069-A | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2005-12-21 | — | — | CN | disclosed |
| US-6762164-B2 | HAIR GROWTH PROMOTING AGENT INCLUDING A CYCLOSPORIN DERIVATIVE AS AN ACTIVE INGREDIENT, AND MORE PARTICULARLY, A HAIR GROWTH PROMOTING AGENT INCLUDING A CYCLOSPORIN A DERIVATIVE SUBSTITUTED IN THE 3-POSITION AS AN ACTIVE INGREDIENT. | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-07-13 | — | — | US | disclosed |
| CN-1507339-A | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2004-06-23 | — | — | CN | disclosed |
| EP-1392224-A1 | THE USE OF NONIMMUNOSUPPRESSIVE EPSILON-HYDROXY-N-METHYL-L-LEUCINE-4 ] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG Household & Health Care Ltd. (KR) | 2004-03-03 | — | — | EP | disclosed |
| EP-1387660-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002092033-A1 | THE USE OF NONIMMUNOSUPPRESSIVE [$G(G)-HYDROXY-N-METHYL-L-LEUCINE4] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092032-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-11-21 | — | — | WO | disclosed |
| EP-0345728-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0376078-A2 | Dye composition for keratinous fiber | KAO CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0345728-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258964-A1 | Skin Cosmetic | CUTA, DEGS1, ALAD | SIRT2 4655/4885 |
| US-20100029787-A1 | Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same | POLD1, FASN, PCNA | SIRT2 3681/4885 |
| US-20110098231-A1 | Skin Cosmetic | CUTA, DEGS1, ALAD | SIRT2 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.