SCHEMBL1628824

SCHEMBL1628824

CCCCCCCCCC1(CCCCCC)CCOO1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030851 0.89 FAAH (0.40)
SCHEMBL2505666 0.78
SCHEMBL18396407 0.77 SIRT2 (0.40) SIRT2
Formaldehyde SCHEMBL9286356 0.73 CPT1A (0.33)
SCHEMBL5140463 0.71 SIRT2 (0.46) SIRT2
SCHEMBL2411591 0.70 TSHR (0.42) SIRT2
SCHEMBL11625298 0.70 TSHR (0.42) SIRT2
SCHEMBL1994954 0.70 TSHR (0.42) SIRT2
SCHEMBL12586891 0.70 TSHR (0.42) SIRT2
SCHEMBL2030187 0.70 TSHR (0.42) SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9048725-A None JP disclosed
EP-1505139-B2 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO CO LTD (JP) 2014-06-18 EP disclosed
EP-1505139-B1 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO CO LTD (JP) 2011-07-13 EP disclosed
US-20110098231-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2011-04-28 US disclosed
US-7927615-B2 Thickener, cosmetic preparation containing the same, and process for producing the same SHISEIDO COMPANY, LTD. (JP) 2011-04-19 US disclosed
EP-2168568-A1 SKIN COSMETIC Shiseido Company, Limited (JP) 2010-03-31 EP disclosed
US-20100029787-A1 Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same SHISEIDO COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20090258964-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2009-10-15 US disclosed
US-20050175564-A1 Tickener, cosmetic preparation containing the same, and process for producing the same SHISEIDO COMPANY, LTD. (JP) 2005-08-11 US disclosed
EP-1505139-A1 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO COMPANY, LTD. (JP) 2005-02-09 EP disclosed
JP-H0948725-A SKIN CLEANING COMPOSITION KANEBO LTD 1997-02-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050175564-A1 Tickener, cosmetic preparation containing the same, and process for producing the same TRHDE, FN1, SAMM50 SIRT2 2225/4885
US-20090258964-A1 Skin Cosmetic CUTA, DEGS1, ALAD SIRT2 4655/4885
US-20100029787-A1 Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same POLD1, FASN, PCNA SIRT2 3681/4885
US-20110098231-A1 Skin Cosmetic CUTA, DEGS1, ALAD SIRT2 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.