Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22134253 | 0.82 | LMNA (0.50) | ALDH1A1LMNAPKMPOLBCNR1 | |
| SCHEMBL23735527 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNACASP2POLBTSHR | |
| SCHEMBL23735522 | 0.76 | CASP2 (0.56) | ALDH1A1LMNACASP2HPGDTSHR | |
| SCHEMBL1769601 | 0.76 | OTC (0.45) | ALDH1A1KMT2A | |
| SCHEMBL1769646 | 0.76 | OTC (0.45) | ALDH1A1KMT2A | |
| SCHEMBL17740222 | 0.74 | CASP2 (0.48) | ALDH1A1LMNACASP2POLBCNR1 | |
| SCHEMBL16281002 | 0.74 | ALDH1A1 (0.45) | ALDH1A1LMNACASP2POLBTSHR | |
| SCHEMBL8414998 | 0.72 | HDAC3 (0.50) | ALDH1A1LMNACASP2POLBTSHR | |
| SCHEMBL17949961 | 0.72 | CASP2 (0.57) | ALDH1A1LMNACASP2HPGDNAAA | |
| SCHEMBL3660629 | 0.72 | LMNA (0.63) | ALDH1A1LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906844-B2 | Immunomodulatory peptides | BIOGEN IDEC HEMOPHILIA INC. (US) | 2014-12-09 | — | — | US | disclosed |