Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16281002 | 0.93 | ALDH1A1 (0.45) | ALDH1A1LMNACASP2KDM4EKDM5C | |
| SCHEMBL17949961 | 0.91 | CASP2 (0.57) | ALDH1A1LMNACASP2MEN1KMT2A | |
| SCHEMBL23735522 | 0.90 | CASP2 (0.56) | ALDH1A1LMNACASP2KDM4ETSHR | |
| SCHEMBL23735431 | 0.90 | FAAH (0.50) | ALDH1A1LMNACASP2TSHRMEN1 | |
| SCHEMBL17740222 | 0.87 | CASP2 (0.48) | ALDH1A1LMNACASP2POLBMEN1 | |
| SCHEMBL8414998 | 0.85 | HDAC3 (0.50) | ALDH1A1LMNACASP2POLBTSHR | |
| SCHEMBL3660629 | 0.85 | LMNA (0.63) | ALDH1A1LMNAKDM4EKDM5CEGLN1 | |
| SCHEMBL23735519 | 0.84 | CASP2 (0.55) | ALDH1A1CASP2TSHRMEN1KMT2A | |
| SCHEMBL27368756 | 0.82 | LMNA (0.44) | ALDH1A1LMNACASP2POLBTSHR | |
| SCHEMBL23735430 | 0.82 | CASP2 (0.54) | ALDH1A1CASP2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |